Basic Information
ID: ALA4836766
Type: Binding
Description: Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by filter binding method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4836766
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 560.68 | 5.86 | 5.86 |
| 396.50 | 2.28 | 2.28 |
| 357.34 | 4.40 | 4.40 |
| 440.47 | 5.39 | 5.39 |
| 359.31 | 3.59 | 3.59 |
| 343.43 | 4.27 | 4.27 |
| 343.31 | 4.40 | 4.40 |
| 401.35 | 3.71 | 3.71 |
| 493.54 | 4.00 | 4.00 |
| 391.78 | 5.05 | 5.05 |
| 290.33 | 2.77 | 2.77 |
| 436.24 | 5.16 | 5.16 |
| 386.38 | 3.64 | 3.64 |
| 317.40 | 4.00 | 4.00 |
| 429.40 | 4.19 | 4.19 |
| 371.37 | 4.71 | 4.71 |
| 375.33 | 4.54 | 4.54 |
| 380.33 | 4.58 | 4.58 |
| 382.39 | 5.26 | 5.26 |
| 372.35 | 3.34 | 3.34 |
| 455.49 | 3.62 | 3.62 |
| 289.34 | 3.38 | 3.38 |
| 396.38 | 4.46 | 4.46 |
| 382.35 | 4.27 | 4.27 |
| 414.39 | 3.51 | 3.51 |
| 358.33 | 3.79 | 3.79 |
| 436.24 | 5.16 | 5.16 |
| 375.33 | 4.54 | 4.54 |
| 345.45 | 4.51 | 4.51 |
| 387.34 | 5.02 | 5.02 |
| 442.45 | 3.71 | 3.71 |
| 431.78 | 5.98 | 5.98 |
| 371.37 | 4.79 | 4.79 |
| 404.37 | 3.72 | 3.72 |
| 447.34 | 6.21 | 6.21 |
| 425.34 | 5.42 | 5.42 |
| 391.38 | 3.32 | 3.32 |
| 345.33 | 4.39 | 4.39 |
| 400.34 | 4.29 | 4.29 |
| 389.36 | 4.85 | 4.85 |
| 407.38 | 2.99 | 2.99 |
| 425.34 | 5.19 | 5.19 |
| 405.81 | 5.44 | 5.44 |
| 371.37 | 4.41 | 4.41 |
| 373.34 | 3.37 | 3.37 |
| 331.42 | 4.50 | 4.50 |
| 387.37 | 3.89 | 3.89 |
| 483.24 | 5.00 | 5.00 |
| 318.38 | 4.26 | 4.26 |
| 307.33 | 3.52 | 3.52 |
| 371.37 | 4.41 | 4.41 |
| 374.39 | 5.13 | 5.13 |
| 321.36 | 3.83 | 3.83 |
| 317.40 | 4.00 | 4.00 |
| 415.33 | 5.47 | 5.47 |