Basic Information
ID: ALA4837034
Type: Binding
Description: Inhibition of human recombinant SIRT3 assessed as inhibition of substrate deacetylation using Gln-Pro-Lys-Lys- (epsilon acetyl) AMC peptide as substrate in presence of NAD+ measured by fluorescence based analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: NAD-dependent deacetylase sirtuin 3(ALA4461)
Document: ALA4834484
Inhibition of human recombinant SIRT3 assessed as inhibition of substrate deacetylation using Gln-Pro-Lys-Lys- (epsilon acetyl) AMC peptide as substrate in presence of NAD+ measured by fluorescence based analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4837034
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 736.80 | 1.82 | 1.82 |
| 410.56 | 3.63 | 3.63 |
| 699.78 | 1.99 | 1.99 |
| 743.83 | 2.01 | 2.01 |
| 667.78 | 3.52 | 3.52 |
| 478.60 | 5.53 | 5.53 |
| 625.70 | 2.35 | 2.35 |
| 505.62 | 4.42 | 4.42 |
| 525.61 | 4.56 | 4.56 |
| 554.65 | 4.02 | 4.02 |