Basic Information
ID: ALA4837035
Type: Binding
Description: Inhibition of human recombinant SIRT2 assessed as inhibition of substrate deacetylation using Gln-Pro-Lys-Lys- (epsilon acetyl) AMC peptide as substrate in presence of NAD+ measured by fluorescence based analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: NAD-dependent deacetylase sirtuin 2(ALA4462)
Document: ALA4834484
Inhibition of human recombinant SIRT2 assessed as inhibition of substrate deacetylation using Gln-Pro-Lys-Lys- (epsilon acetyl) AMC peptide as substrate in presence of NAD+ measured by fluorescence based analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4837035
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 498.59 | 5.67 | 5.67 |
| 736.80 | 1.82 | 1.82 |
| 802.92 | 3.73 | 3.73 |
| 680.74 | 3.47 | 3.47 |
| 822.91 | 3.87 | 3.87 |
| 410.56 | 3.63 | 3.63 |
| 834.92 | 2.20 | 2.20 |
| 878.97 | 2.21 | 2.21 |
| 699.78 | 1.99 | 1.99 |
| 510.59 | 4.00 | 4.00 |
| 743.83 | 2.01 | 2.01 |
| 687.77 | 3.66 | 3.66 |
| 692.75 | 1.80 | 1.80 |
| 463.53 | 3.25 | 3.25 |
| 667.78 | 3.52 | 3.52 |
| 537.61 | 2.90 | 2.90 |
| 478.60 | 5.53 | 5.53 |
| 760.84 | 2.55 | 2.55 |
| 581.67 | 2.91 | 2.91 |
| 436.52 | 4.36 | 4.36 |
| 625.70 | 2.35 | 2.35 |
| 505.62 | 4.42 | 4.42 |
| 525.61 | 4.56 | 4.56 |
| 554.65 | 4.02 | 4.02 |
| 618.67 | 2.16 | 2.16 |
| 660.75 | 3.33 | 3.33 |