Basic Information
ID: ALA4837136
Type: Binding
Description: Inhibition of N-terminal 6XHis-tagged Clostridium botulinum BoNT/A light chain C-terminal truncation mutant (1 to 425 residues) expressed in Escherichia coli using SNAPtide as substrate preincubated with enzyme for 30 mins followed by substrate addition by FRET assay
Format: BAO_0000019
Organism: Clostridium botulinum
Target: Botulinum neurotoxin type A(ALA5192)
Document: ALA4834496
Inhibition of N-terminal 6XHis-tagged Clostridium botulinum BoNT/A light chain C-terminal truncation mutant (1 to 425 residues) expressed in Escherichia coli using SNAPtide as substrate preincubated with enzyme for 30 mins followed by substrate addition by FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4837136
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.26 | 4.31 | 4.31 |
| 395.29 | 4.56 | 4.56 |
| 396.27 | 3.26 | 3.26 |
| 396.27 | 3.26 | 3.26 |
| 381.26 | 4.31 | 4.31 |
| 382.25 | 3.58 | 3.58 |
| 382.25 | 3.58 | 3.58 |
| 367.23 | 4.00 | 4.00 |
| 397.26 | 3.38 | 3.38 |
| 381.26 | 4.31 | 4.31 |
| 383.23 | 3.71 | 3.71 |
| 383.23 | 3.71 | 3.71 |
| 395.29 | 3.99 | 3.99 |
| 395.29 | 3.99 | 3.99 |
| 397.26 | 3.38 | 3.38 |
| 381.26 | 3.68 | 3.68 |
| 409.31 | 4.24 | 4.24 |
| 397.26 | 3.38 | 3.38 |
| 382.25 | 3.58 | 3.58 |
| 396.27 | 3.26 | 3.26 |
| 383.23 | 3.71 | 3.71 |
| 395.29 | 3.99 | 3.99 |