Basic Information
ID: ALA4837172
Type: Binding
Description: Positive allosteric modulator activity at rat mGlu3 receptor transfected in GIRK channel overexpressing cells assessed as potentiation of glutamate-induced response by thallium mobilization assay
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4837172
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 448.94 | 5.91 | 5.91 |
| 444.52 | 5.26 | 5.26 |
| 444.52 | 5.12 | 5.12 |
| 432.49 | 5.25 | 5.25 |
| 400.52 | 5.42 | 5.42 |
| 444.52 | 5.12 | 5.12 |
| 425.53 | 4.66 | 4.66 |
| 432.49 | 5.25 | 5.25 |
| 418.46 | 5.00 | 5.00 |
| 459.56 | 5.40 | 5.40 |
| 444.52 | 5.12 | 5.12 |
| 445.53 | 5.06 | 5.06 |
| 444.52 | 5.26 | 5.26 |
| 444.52 | 5.12 | 5.12 |
| 428.53 | 5.42 | 5.42 |
| 432.49 | 5.39 | 5.39 |
| 430.50 | 4.87 | 4.87 |
| 415.49 | 4.65 | 4.65 |
| 430.50 | 4.87 | 4.87 |
| 430.50 | 4.87 | 4.87 |
| 428.53 | 5.42 | 5.42 |
| 471.59 | 5.12 | 5.12 |
| 448.94 | 5.77 | 5.77 |
| 418.46 | 5.00 | 5.00 |
| 418.46 | 5.00 | 5.00 |
| 429.51 | 4.96 | 4.96 |
| 430.50 | 4.87 | 4.87 |
| 400.52 | 5.57 | 5.57 |
| 428.53 | 5.56 | 5.56 |
| 431.50 | 4.80 | 4.80 |
| 448.94 | 5.77 | 5.77 |
| 432.49 | 5.39 | 5.39 |
| 428.53 | 5.42 | 5.42 |
| 448.94 | 5.77 | 5.77 |
| 432.49 | 5.25 | 5.25 |
| 446.52 | 5.48 | 5.48 |
| 432.49 | 5.25 | 5.25 |
| 432.49 | 5.25 | 5.25 |
| 418.46 | 5.00 | 5.00 |
| 428.53 | 5.56 | 5.56 |
| 400.52 | 5.42 | 5.42 |