ID: ALA4837173
Type: Binding
Description: Positive allosteric modulator activity at rat mGlu2 receptor transfected in GIRK channel overexpressing cells assessed as potentiation of glutamate-induced response by thallium mobilization assay
Organism: Rattus norvegicus
Bioactivity
Activity Types for Assay ALA4837173
EC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
448.94 | 5.91 | 5.91 |
444.52 | 5.26 | 5.26 |
432.49 | 5.25 | 5.25 |
400.52 | 5.42 | 5.42 |
444.52 | 5.12 | 5.12 |
425.53 | 4.66 | 4.66 |
432.49 | 5.25 | 5.25 |
418.46 | 5.00 | 5.00 |
459.56 | 5.40 | 5.40 |
444.52 | 5.12 | 5.12 |
445.53 | 5.06 | 5.06 |
444.52 | 5.26 | 5.26 |
444.52 | 5.12 | 5.12 |
428.53 | 5.42 | 5.42 |
432.49 | 5.39 | 5.39 |
430.50 | 4.87 | 4.87 |
415.49 | 4.65 | 4.65 |
430.50 | 4.87 | 4.87 |
428.53 | 5.42 | 5.42 |
471.59 | 5.12 | 5.12 |
448.94 | 5.77 | 5.77 |
418.46 | 5.00 | 5.00 |
418.46 | 5.00 | 5.00 |
429.51 | 4.96 | 4.96 |
400.52 | 5.57 | 5.57 |
428.53 | 5.56 | 5.56 |
431.50 | 4.80 | 4.80 |
448.94 | 5.77 | 5.77 |
432.49 | 5.39 | 5.39 |
448.94 | 5.77 | 5.77 |
432.49 | 5.25 | 5.25 |
432.49 | 5.25 | 5.25 |
418.46 | 5.00 | 5.00 |
428.53 | 5.56 | 5.56 |
400.52 | 5.42 | 5.42 |