Assay Report Card

Basic Information

ID: ALA4837174

Type: Binding

Description: Positive allosteric modulator activity at rat mGlu3 receptor transfected in GIRK channel overexpressing cells assessed as potentiation of glutamate-induced response by thallium mobilization assay relative to glutamate

Organism: Rattus norvegicus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
448.945.915.91
444.525.265.26
444.525.125.12
432.495.255.25
400.525.425.42
444.525.125.12
425.534.664.66
432.495.255.25
418.465.005.00
459.565.405.40
444.525.125.12
445.535.065.06
444.525.265.26
444.525.125.12
428.535.425.42
432.495.395.39
430.504.874.87
415.494.654.65
430.504.874.87
430.504.874.87
428.535.425.42
471.595.125.12
448.945.775.77
418.465.005.00
418.465.005.00
429.514.964.96
430.504.874.87
400.525.575.57
428.535.565.56
431.504.804.80
448.945.775.77
432.495.395.39
428.535.425.42
448.945.775.77
432.495.255.25
446.525.485.48
432.495.255.25
432.495.255.25
418.465.005.00
428.535.565.56
400.525.425.42