Basic Information
ID: ALA4837910
Type: Binding
Description: Inhibition of ASK1 in human HEK293 cells transfected with AP1 assessed as inhibition of AP1-induced firefly luciferase activity preincubated for 1 hr followed by PMA stimulation and measured after 6 hrs by luciferase reporter assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4837910
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 445.50 | 4.68 | 4.68 |
| 410.49 | 4.53 | 4.53 |
| 346.39 | 3.17 | 3.17 |
| 441.54 | 5.49 | 5.49 |
| 409.50 | 5.13 | 5.13 |
| 494.60 | 4.97 | 4.97 |
| 426.48 | 4.06 | 4.06 |
| 410.50 | 3.83 | 3.83 |
| 383.46 | 4.47 | 4.47 |
| 423.52 | 5.44 | 5.44 |
| 453.55 | 5.28 | 5.28 |
| 421.51 | 5.28 | 5.28 |
| 435.54 | 5.67 | 5.67 |
| 413.49 | 4.54 | 4.54 |
| 407.48 | 4.89 | 4.89 |
| 439.52 | 5.14 | 5.14 |