Potency index, ratio of DRV Ki to test compound Ki for inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys...

Basic Information

ID: ALA4837934

Type: Binding

Description: Potency index, ratio of DRV Ki to test compound Ki for inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mins followed by substrate addition and measured for 10 mins by FRET assay

Format: BAO_0000357

Organism: Human immunodeficiency virus 1

Target:  Human immunodeficiency virus type 1 protease(ALA243)

Document:  ALA4837199

Potency index, ratio of DRV Ki to test compound Ki for inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mins followed by substrate addition and measured for 10 mins by FRET assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
517.692.432.43