Basic Information
ID: ALA4838416
Type: Functional
Description: Antileishmanial activity against amastigote stage of Leishmania donovani MHOM/IN/80/Dd8 harboring luciferase gene infected in mouse J774 cells assessed as parasite growth inhibition at 25 uM incubated for 72 hrs by Steady-Glo reagent based luciferase assay
Format: BAO_0000218
Organism: Leishmania donovani
Strain: MHOM/IN/80/Dd8
Cell type: J774
Target: Leishmania donovani(ALA367)
Document: ALA4837217
Antileishmanial activity against amastigote stage of Leishmania donovani MHOM/IN/80/Dd8 harboring luciferase gene infected in mouse J774 cells assessed as parasite growth inhibition at 25 uM incubated for 72 hrs by Steady-Glo reagent based luciferase assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4838416
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 407.58 | 5.68 | 5.68 |
| 403.44 | 3.22 | 3.22 |
| 399.45 | 3.31 | 3.31 |
| 425.56 | 4.91 | 4.91 |
| 373.41 | 3.21 | 3.21 |
| 391.86 | 4.16 | 4.16 |
| 419.58 | 5.07 | 5.07 |
| 385.42 | 3.11 | 3.11 |
| 387.44 | 3.52 | 3.52 |
| 407.86 | 3.86 | 3.86 |
| 452.31 | 3.97 | 3.97 |
| 458.34 | 4.03 | 4.03 |
| 393.47 | 3.58 | 3.58 |
| 466.33 | 4.28 | 4.28 |
| 426.30 | 4.81 | 4.81 |
| 391.86 | 4.16 | 4.16 |
| 423.47 | 4.36 | 4.36 |
| 421.88 | 4.17 | 4.17 |
| 413.55 | 5.00 | 5.00 |
| 379.44 | 3.27 | 3.27 |
| 433.60 | 5.11 | 5.11 |
| 506.47 | 5.81 | 5.81 |
| 470.75 | 4.92 | 4.92 |