Basic Information
ID: ALA4838587
Type: Binding
Description: Inhibition of mouse GAT4 expressed in human HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 40 mins by LC-ESI-MS/MS analysis
Organism: Mus musculus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4838587
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 505.61 | 4.82 | 4.82 |
| 463.02 | 5.16 | 5.16 |
| 462.04 | 5.13 | 5.13 |
| 403.61 | 5.82 | 5.82 |
| 419.31 | 4.73 | 4.73 |
| 544.19 | 6.04 | 6.04 |
| 461.01 | 5.14 | 5.14 |
| 452.60 | 4.99 | 4.99 |
| 530.11 | 5.40 | 5.40 |
| 487.04 | 5.64 | 5.64 |
| 440.59 | 4.80 | 4.80 |
| 466.63 | 5.30 | 5.30 |
| 495.67 | 4.75 | 4.75 |
| 530.11 | 5.40 | 5.40 |
| 471.62 | 4.71 | 4.71 |
| 513.66 | 4.89 | 4.89 |
| 453.63 | 4.57 | 4.57 |
| 468.64 | 4.91 | 4.91 |
| 489.06 | 5.26 | 5.26 |
| 472.60 | 4.75 | 4.75 |
| 488.08 | 5.23 | 5.23 |
| 579.69 | 6.29 | 6.29 |
| 509.69 | 5.06 | 5.06 |
| 467.66 | 4.88 | 4.88 |
| 454.61 | 4.61 | 4.61 |
| 487.04 | 5.64 | 5.64 |
| 489.06 | 5.26 | 5.26 |
| 426.56 | 4.49 | 4.49 |
| 444.55 | 4.63 | 4.63 |
| 470.59 | 5.13 | 5.13 |
| 488.08 | 5.23 | 5.23 |
| 461.01 | 5.14 | 5.14 |