Assay Report Card

Basic Information

ID: ALA4838806

Type: Functional

Description: Potentiation of ponatinib-induced apoptosis human KBM5 cells expressing T315I mutant assessed as increase in apoptotic cells at 5 nM measured after 48 hrs by annexin V staining based flow cytometry analysis (Rvb = 35 %)

Organism: Homo sapiens

Cell type: KBM5

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
433.535.775.77