Basic Information
ID: ALA4838808
Type: Functional
Description: Potentiation of ponatinib-induced mitochondrial membrane depolarization in human KBM5 cells expressing T315I mutant at 5 nM in the presence of ponatinib measured upto 48 hrs by JC-1 staining based flow cytometry analysis (Rvb= 32.7 %)
Organism: Homo sapiens
Cell type: KBM5
Activity Charts
Bioactivity
Activity Types for Assay ALA4838808
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 433.53 | 5.77 | 5.77 |