Assay Report Card

Basic Information

ID: ALA4838809

Type: Binding

Description: Inhibition of Bcr-Abl tyrosine phosphorylation in human KBM5 cells expressing T315I mutant at 1 to 10 nM in the presence of ponatinib measured after 24 hrs by western blot analysis

Organism: Homo sapiens

Cell type: KBM5

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
433.535.775.77