Assay Report Card

Basic Information

ID: ALA4838854

Type: Binding

Description: Potency index, ratio of oseltamivir carboxylate IC50 to test compound IC50 for inhibition of Influenza A virus (A/California/04/2009 (H1N1)) Neuraminidase H274Y mutant using MUNANA as substrate preincubated for 5 to 15 mins followed by substrate addition and measured after 30 mins by fluorescence spectrophotometric method

Organism: Influenza A virus (A/California/04/2009(H1N1))

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
327.380.520.52
356.420.280.28
398.501.451.45
342.400.020.02
384.481.061.06