Basic Information
ID: ALA4839233
Type: Functional
Description: Agonist activity at N-terminal HA-tagged human TGR5 expressed in HEK293 cells assessed as reduction in intracellular cAMP levels incubated for 30 mins by Lance Ultra cAMP assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4839233
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 408.58 | 3.45 | 3.45 |
| 376.58 | 5.51 | 5.51 |
| 453.40 | 6.07 | 6.07 |
| 399.28 | 5.77 | 5.77 |
| 543.83 | 8.31 | 8.31 |
| 570.82 | 7.43 | 7.43 |
| 567.82 | 8.15 | 8.15 |
| 541.82 | 8.07 | 8.07 |
| 613.88 | 7.12 | 7.12 |
| 512.82 | 7.69 | 7.69 |
| 571.84 | 7.65 | 7.65 |
| 501.75 | 7.27 | 7.27 |
| 598.87 | 7.18 | 7.18 |
| 565.77 | 6.79 | 6.79 |
| 564.87 | 7.93 | 7.93 |
| 607.88 | 9.43 | 9.43 |
| 529.81 | 7.92 | 7.92 |
| 515.78 | 7.53 | 7.53 |
| 530.79 | 7.37 | 7.37 |
| 599.85 | 7.61 | 7.61 |
| 543.79 | 6.79 | 6.79 |
| 565.86 | 7.05 | 7.05 |
| 551.83 | 6.66 | 6.66 |
| 436.63 | 3.94 | 3.94 |
| 530.79 | 8.35 | 8.35 |
| 569.87 | 8.85 | 8.85 |
| 541.77 | 7.00 | 7.00 |
| 555.84 | 8.46 | 8.46 |
| 543.79 | 6.79 | 6.79 |
| 528.82 | 8.52 | 8.52 |
| 543.83 | 8.31 | 8.31 |
| 516.76 | 6.71 | 6.71 |
| 555.80 | 7.20 | 7.20 |
| 543.83 | 8.27 | 8.27 |
| 595.84 | 9.56 | 9.56 |
| 614.87 | 7.54 | 7.54 |