Basic Information
ID: ALA4839255
Type: Functional
Description: Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO-K1
Target: Type-1 angiotensin II receptor(ALA227)
Document: ALA4837242
Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4839255
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 406.53 | 4.81 | 4.81 |
| 438.53 | 5.35 | 5.35 |
| 424.50 | 5.15 | 5.15 |
| 418.54 | 5.69 | 5.69 |
| 404.51 | 5.30 | 5.30 |
| 428.54 | 4.78 | 4.78 |
| 452.55 | 5.74 | 5.74 |
| 416.53 | 3.86 | 3.86 |
| 464.57 | 5.38 | 5.38 |
| 404.52 | 3.76 | 3.76 |
| 416.53 | 3.86 | 3.86 |
| 430.56 | 4.88 | 4.88 |
| 402.50 | 4.24 | 4.24 |