Basic Information
ID: ALA4839299
Type: ADME
Description: Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate preincubated for 15 mins followed by NADPH addition and measured after 8 mins by LC-MS/MS analysis
Format: BAO_0000220
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 2C9(ALA3397)
Document: ALA4837245
Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate preincubated for 15 mins followed by NADPH addition and measured after 8 mins by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4839299
INH
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 432.49 | 4.11 | 4.11 |
| 432.97 | 4.49 | 4.49 |
| 414.50 | 3.97 | 3.97 |
| 430.96 | 4.49 | 4.49 |
| 434.50 | 4.11 | 4.11 |
| 378.52 | 3.69 | 3.69 |