Basic Information
ID: ALA4839301
Type: ADME
Description: Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 15 mins followed by NADPH addition and measured after 8 mins by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4839301
INH
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 432.49 | 4.11 | 4.11 |
| 432.97 | 4.49 | 4.49 |
| 414.50 | 3.97 | 3.97 |
| 430.96 | 4.49 | 4.49 |
| 434.50 | 4.11 | 4.11 |
| 378.52 | 3.69 | 3.69 |