Basic Information
ID: ALA4839365
Type: Binding
Description: Inhibition of full-length N-terminal FLAG-tagged human ATM expressed in HEK293-6E cells using biotin-PEG2-SVEPPLSQETFSD as substrate preincubated for 15 mins followed by substrate addition and measured after 90 mins in presence of ATP by TR-FRET assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK2936E
Target: Serine-protein kinase ATM(ALA3797)
Document: ALA4837246
Inhibition of full-length N-terminal FLAG-tagged human ATM expressed in HEK293-6E cells using biotin-PEG2-SVEPPLSQETFSD as substrate preincubated for 15 mins followed by substrate addition and measured after 90 mins in presence of ATP by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4839365
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 395.41 | 4.48 | 4.48 |
| 379.37 | 4.08 | 4.08 |
| 399.38 | 4.31 | 4.31 |
| 409.44 | 4.95 | 4.95 |
| 409.47 | 2.64 | 2.64 |
| 393.40 | 4.47 | 4.47 |
| 394.43 | 5.08 | 5.08 |
| 345.41 | 3.54 | 3.54 |
| 409.47 | 2.49 | 2.49 |
| 409.44 | 4.95 | 4.95 |
| 360.42 | 3.33 | 3.33 |
| 391.43 | 5.62 | 5.62 |
| 364.84 | 4.49 | 4.49 |
| 410.46 | 1.88 | 1.88 |
| 380.40 | 4.78 | 4.78 |
| 363.40 | 3.68 | 3.68 |
| 426.47 | 3.38 | 3.38 |
| 381.39 | 4.17 | 4.17 |
| 399.38 | 4.25 | 4.25 |
| 394.43 | 5.02 | 5.02 |
| 380.40 | 5.00 | 5.00 |
| 394.43 | 5.02 | 5.02 |
| 377.40 | 4.79 | 4.79 |
| 379.37 | 3.64 | 3.64 |
| 408.48 | 3.24 | 3.24 |
| 377.40 | 5.23 | 5.23 |
| 432.53 | 3.56 | 3.56 |
| 380.40 | 4.78 | 4.78 |
| 414.39 | 4.74 | 4.74 |
| 399.38 | 4.31 | 4.31 |