Basic Information
ID: ALA4839497
Type: Functional
Description: Antiallergic activity against anti-DNP-IgE sensitized rat RBL-2H3 cells assessed as induction of degranulation by measuring beta-hexosaminidase release using P-nitrophenyl-N-acetyl-D-glucosamide as substrate at 0.04 uM measured after 1 hr by microplate reader relative to control
Organism: Rattus norvegicus
Cell type: RBL-2H3
Activity Charts
Bioactivity
Activity Types for Assay ALA4839497
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 387.44 | 3.64 | 3.64 |
| 441.92 | 4.68 | 4.68 |
| 437.50 | 4.03 | 4.03 |
| 476.37 | 5.33 | 5.33 |
| 437.50 | 4.03 | 4.03 |
| 421.88 | 4.29 | 4.29 |
| 430.46 | 2.74 | 2.74 |
| 407.48 | 4.02 | 4.02 |
| 521.50 | 4.75 | 4.75 |
| 483.53 | 3.74 | 3.74 |
| 453.50 | 3.73 | 3.73 |
| 471.49 | 3.87 | 3.87 |
| 495.58 | 4.86 | 4.86 |
| 441.92 | 4.68 | 4.68 |
| 475.47 | 5.04 | 5.04 |
| 437.50 | 4.03 | 4.03 |
| 467.53 | 4.04 | 4.04 |
| 487.95 | 4.39 | 4.39 |
| 441.92 | 4.68 | 4.68 |
| 444.49 | 3.00 | 3.00 |
| 475.47 | 5.04 | 5.04 |
| 543.47 | 6.06 | 6.06 |
| 467.53 | 4.04 | 4.04 |
| 491.47 | 4.92 | 4.92 |
| 467.53 | 4.04 | 4.04 |
| 491.47 | 4.92 | 4.92 |
| 497.56 | 4.05 | 4.05 |
| 495.58 | 4.89 | 4.89 |
| 408.47 | 3.42 | 3.42 |
| 543.47 | 6.06 | 6.06 |
| 483.53 | 3.74 | 3.74 |
| 471.49 | 3.87 | 3.87 |
| 465.51 | 3.80 | 3.80 |
| 413.53 | 3.84 | 3.84 |
| 532.40 | 4.50 | 4.50 |
| 509.92 | 5.70 | 5.70 |