Basic Information
ID: ALA4839804
Type: Binding
Description: Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight by ELISA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: H4
Target: Gamma-secretase(ALA2094135)
Document: ALA4837257
Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4839804
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 389.42 | 3.35 | 3.35 |
| 363.42 | 2.92 | 2.92 |
| 423.90 | 4.04 | 4.04 |
| 415.86 | 3.79 | 3.79 |
| 417.39 | 3.63 | 3.63 |
| 418.28 | 3.91 | 3.91 |
| 417.39 | 3.63 | 3.63 |
| 377.45 | 3.39 | 3.39 |
| 383.84 | 3.26 | 3.26 |
| 397.87 | 3.57 | 3.57 |
| 397.87 | 3.65 | 3.65 |
| 405.50 | 3.90 | 3.90 |
| 367.38 | 2.75 | 2.75 |
| 418.28 | 3.91 | 3.91 |
| 435.38 | 3.76 | 3.76 |
| 383.84 | 3.26 | 3.26 |
| 423.90 | 4.14 | 4.14 |
| 379.42 | 2.62 | 2.62 |
| 432.31 | 4.30 | 4.30 |
| 389.46 | 3.48 | 3.48 |
| 451.84 | 4.28 | 4.28 |
| 374.40 | 2.48 | 2.48 |
| 423.90 | 4.14 | 4.14 |
| 349.39 | 2.61 | 2.61 |
| 374.40 | 2.48 | 2.48 |
| 451.84 | 4.28 | 4.28 |
| 411.89 | 4.04 | 4.04 |
| 397.87 | 3.65 | 3.65 |
| 401.83 | 3.40 | 3.40 |
| 389.46 | 3.48 | 3.48 |
| 435.38 | 3.76 | 3.76 |
| 397.87 | 3.57 | 3.57 |
| 379.42 | 2.62 | 2.62 |
| 401.83 | 3.40 | 3.40 |