Assay Report Card

Basic Information

ID: ALA4839807

Type: Functional

Description: Invivo modulation of gamma secretase in mouse assessed as reduction in Abeta42 levels in brain at 30 mg/kg, po measured after 6 hrs relative to control

Organism: Mus musculus

Tissue: Brain

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
389.423.353.35
423.904.044.04
415.863.793.79
417.393.633.63
418.283.913.91
397.873.573.57
397.873.653.65
418.283.913.91
435.383.763.76
383.843.263.26
401.833.403.40
401.833.403.40