Basic Information
ID: ALA4839807
Type: Functional
Description: Invivo modulation of gamma secretase in mouse assessed as reduction in Abeta42 levels in brain at 30 mg/kg, po measured after 6 hrs relative to control
Format: BAO_0000218
Organism: Mus musculus
Tissue: Brain
Target: Mus musculus(ALA375)
Document: ALA4837257
Invivo modulation of gamma secretase in mouse assessed as reduction in Abeta42 levels in brain at 30 mg/kg, po measured after 6 hrs relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4839807
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 389.42 | 3.35 | 3.35 |
| 423.90 | 4.04 | 4.04 |
| 415.86 | 3.79 | 3.79 |
| 417.39 | 3.63 | 3.63 |
| 418.28 | 3.91 | 3.91 |
| 397.87 | 3.57 | 3.57 |
| 397.87 | 3.65 | 3.65 |
| 418.28 | 3.91 | 3.91 |
| 435.38 | 3.76 | 3.76 |
| 383.84 | 3.26 | 3.26 |
| 401.83 | 3.40 | 3.40 |
| 401.83 | 3.40 | 3.40 |