Basic Information
ID: ALA4839808
Type: ADME
Description: Ratio of of free drug concentration in rat brain to EC90 for modulation of gamma secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight by ELISA
Activity Charts
Bioactivity
Activity Types for Assay ALA4839808
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 389.42 | 3.35 | 3.35 |
| 423.90 | 4.04 | 4.04 |
| 415.86 | 3.79 | 3.79 |
| 397.87 | 3.65 | 3.65 |