Assay Report Card

Basic Information

ID: ALA4839810

Type: Functional

Description: Invivo modulation of gamma secretase in rat assessed as reduction in Abeta42 levels in CSF at 30 mg/kg, po measured after 6 hrs by ELISA relative to control

Organism: Rattus norvegicus

Tissue: Cerebrospinal fluid

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
389.423.353.35
423.904.044.04
415.863.793.79
397.873.653.65