Basic Information
ID: ALA4840127
Type: ADME
Description: Inhibition of CYP2D6 (unknown origin) assessed as bufuralol hydroxylation to 4'-hydroxy bufuralol at 10 uM by cocktail inhibition assay relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: Cytochrome P450 2D6(ALA289)
Document: ALA4837263
Inhibition of CYP2D6 (unknown origin) assessed as bufuralol hydroxylation to 4'-hydroxy bufuralol at 10 uM by cocktail inhibition assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4840127
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 417.88 | 3.36 | 3.36 |
| 457.92 | 4.46 | 4.46 |
| 442.90 | 4.75 | 4.75 |
| 383.86 | 4.24 | 4.24 |
| 401.85 | 4.38 | 4.38 |
| 415.88 | 4.69 | 4.69 |
| 383.86 | 4.89 | 4.89 |
| 425.90 | 4.01 | 4.01 |
| 400.87 | 4.98 | 4.98 |