Basic Information
ID: ALA4840154
Type: Binding
Description: Inhibition of human recombinant full length N-terminal GST tagged MEK4 expressed in Sf21 cells using p38 alpha as substrate pre-incubated for 30 mins followed by addition of ATP and measured after 150 mins by ADP-Glo kinase assay
Organism: Homo sapiens
Cell type: Sf21
Activity Charts
Bioactivity
Activity Types for Assay ALA4840154
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 503.40 | 6.21 | 6.21 |
| 397.43 | 4.18 | 4.18 |
| 227.24 | 2.95 | 2.95 |
| 308.23 | 4.11 | 4.11 |
| 256.24 | 3.07 | 3.07 |
| 212.23 | 3.37 | 3.37 |
| 259.26 | 3.45 | 3.45 |
| 435.40 | 5.19 | 5.19 |
| 385.39 | 4.31 | 4.31 |
| 409.49 | 5.29 | 5.29 |
| 392.42 | 4.04 | 4.04 |
| 275.26 | 3.16 | 3.16 |
| 367.40 | 4.17 | 4.17 |
| 329.76 | 4.10 | 4.10 |
| 331.37 | 2.81 | 2.81 |
| 283.31 | 3.72 | 3.72 |
| 331.37 | 3.27 | 3.27 |
| 305.33 | 2.74 | 2.74 |
| 381.43 | 4.48 | 4.48 |
| 373.45 | 3.98 | 3.98 |
| 281.29 | 3.49 | 3.49 |
| 373.45 | 4.44 | 4.44 |
| 291.31 | 2.02 | 2.02 |
| 445.50 | 3.57 | 3.57 |
| 436.30 | 5.48 | 5.48 |
| 271.30 | 3.32 | 3.32 |
| 410.43 | 3.27 | 3.27 |
| 446.49 | 2.82 | 2.82 |
| 401.85 | 4.82 | 4.82 |
| 331.37 | 3.27 | 3.27 |
| 368.39 | 3.56 | 3.56 |
| 331.37 | 2.81 | 2.81 |
| 368.39 | 3.56 | 3.56 |
| 373.45 | 4.44 | 4.44 |
| 367.40 | 4.17 | 4.17 |
| 338.39 | 3.43 | 3.43 |
| 397.43 | 4.18 | 4.18 |
| 373.45 | 3.98 | 3.98 |
| 285.28 | 3.04 | 3.04 |
| 368.39 | 3.56 | 3.56 |
| 409.44 | 4.37 | 4.37 |
| 425.49 | 4.96 | 4.96 |
| 291.31 | 2.02 | 2.02 |