Basic Information
ID: ALA4840200
Type: Binding
Description: Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with CCL2-promoter luciferase plasmid construct assessed as reduction in IL-1 beta induced inflammation by luciferase reporter gene assay
Organism: Rattus norvegicus
Cell type: INS-1 832/13
Activity Charts
Bioactivity
Activity Types for Assay ALA4840200
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 388.49 | 5.49 | 5.49 |
| 420.50 | 5.80 | 5.80 |
| 368.50 | 5.16 | 5.16 |
| 340.44 | 4.53 | 4.53 |
| 326.42 | 4.14 | 4.14 |
| 406.48 | 5.63 | 5.63 |
| 454.49 | 5.78 | 5.78 |
| 392.47 | 1.90 | 1.90 |
| 362.47 | 1.78 | 1.78 |
| 394.51 | 5.55 | 5.55 |
| 400.52 | 5.36 | 5.36 |
| 398.55 | 5.83 | 5.83 |
| 416.54 | 5.97 | 5.97 |
| 468.52 | 5.95 | 5.95 |
| 352.48 | 4.40 | 4.40 |
| 336.48 | 4.70 | 4.70 |
| 402.51 | 5.67 | 5.67 |
| 418.51 | 5.50 | 5.50 |
| 452.50 | 5.26 | 5.26 |
| 384.52 | 5.66 | 5.66 |
| 338.45 | 4.01 | 4.01 |
| 406.55 | 5.42 | 5.42 |
| 402.51 | 5.80 | 5.80 |
| 432.54 | 5.67 | 5.67 |
| 351.43 | 4.03 | 4.03 |
| 480.56 | 5.82 | 5.82 |
| 450.53 | 5.73 | 5.73 |
| 450.53 | 5.95 | 5.95 |
| 420.58 | 5.60 | 5.60 |
| 404.58 | 5.90 | 5.90 |
| 408.54 | 5.73 | 5.73 |
| 390.55 | 5.72 | 5.72 |
| 414.55 | 5.53 | 5.53 |
| 322.45 | 4.31 | 4.31 |