Assay Report Card

Basic Information

ID: ALA4840233

Type: Binding

Description: Protac activity at VHL/CDK4 in human MM1.S cells assessed as induction of CDK4 degradation at 0.1 to 1 uM measured after 16 hrs by Western blotting analysis

Organism: Homo sapiens

Cell type: MM1.S

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
273.25-0.33-0.33
936.042.362.36
936.042.242.24
994.081.441.44
964.051.561.56
1080.30