Ratio of JO146 IC50 to test compound IC50 for inhibition of recombinant ctHtrA serine protease using Me0Coum-ENLHLPLPI1F-D as substrate pretreated for...

Basic Information

ID: ALA4840819

Type: Binding

Description: Ratio of JO146 IC50 to test compound IC50 for inhibition of recombinant ctHtrA serine protease using Me0Coum-ENLHLPLPI1F-D as substrate pretreated for 10 minutes followed by substrate addition and measured after 30 minutes

Format: BAO_0000357

Organism: Chlamydia trachomatis

Target:  Probable periplasmic serine endoprotease DegP-like(ALA4888439)

Document:  ALA4840314

Ratio of JO146 IC50 to test compound IC50 for inhibition of recombinant ctHtrA serine protease using Me0Coum-ENLHLPLPI1F-D as substrate pretreated for 10 minutes followed by substrate addition and measured after 30 minutes: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
601.685.985.98
629.746.766.76
615.716.376.37
663.757.167.16
583.626.606.60
614.725.945.94
603.616.866.86
603.616.866.86
589.596.476.47
613.746.396.39
575.565.915.91
628.756.336.33
569.606.216.21
589.596.306.30
649.736.776.77