Basic Information
ID: ALA4840820
Type: Binding
Description: Ratio of JO146 IC50 to test compound IC50 for inhibition of human neutrophil elastase using methoxysuccinyl-Ala-Ala-Pro-Val-pNA as substrate incubated for 15 min
Format: BAO_0000221
Organism: Homo sapiens
Cell type: Neutrophil
Target: Leukocyte elastase(ALA248)
Document: ALA4840314
Ratio of JO146 IC50 to test compound IC50 for inhibition of human neutrophil elastase using methoxysuccinyl-Ala-Ala-Pro-Val-pNA as substrate incubated for 15 min: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4840820
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 601.68 | 5.98 | 5.98 |
| 629.74 | 6.76 | 6.76 |
| 615.71 | 6.37 | 6.37 |
| 663.75 | 7.16 | 7.16 |
| 583.62 | 6.60 | 6.60 |
| 614.72 | 5.94 | 5.94 |
| 603.61 | 6.86 | 6.86 |
| 589.59 | 6.47 | 6.47 |
| 603.61 | 6.86 | 6.86 |
| 589.59 | 6.47 | 6.47 |
| 613.74 | 6.39 | 6.39 |
| 575.56 | 5.91 | 5.91 |
| 628.75 | 6.33 | 6.33 |
| 569.60 | 6.21 | 6.21 |
| 589.59 | 6.30 | 6.30 |
| 649.73 | 6.77 | 6.77 |