Basic Information
ID: ALA4840847
Type: Binding
Description: Inhibition of mPGES-1 obtained from IL-beta stimulated human A549 cells microsomes assessed as residual activity by measuring conversion of PGH2 to PGE2 at 10 uM by cell-free RP-HPLC method
Format: BAO_0000251
Organism: Homo sapiens
Cell type: A549
Subcellular Fraction: Microsome
Target: Prostaglandin E synthase(ALA5658)
Document: ALA4840316
Inhibition of mPGES-1 obtained from IL-beta stimulated human A549 cells microsomes assessed as residual activity by measuring conversion of PGH2 to PGE2 at 10 uM by cell-free RP-HPLC method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4840847
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 320.37 | 4.84 | 4.84 |
| 349.42 | 4.22 | 4.22 |
| 348.43 | 4.96 | 4.96 |
| 343.41 | 5.61 | 5.61 |
| 335.39 | 4.42 | 4.42 |
| 374.34 | 5.26 | 5.26 |
| 348.43 | 5.32 | 5.32 |
| 377.47 | 4.59 | 4.59 |
| 355.42 | 3.12 | 3.12 |
| 363.44 | 4.41 | 4.41 |
| 348.43 | 4.55 | 4.55 |