Basic Information
ID: ALA4840850
Type: Binding
Description: Inhibition of 5-LO in A23187/AA-stimulated human intact neutrophils assessed as reduction in LTB4/5-HETE formation by measuring residual activity at 10 uM measured after 20 mins by RP-HPLC method
Format: BAO_0000221
Organism: Homo sapiens
Cell type: Neutrophil
Target: Arachidonate 5-lipoxygenase(ALA215)
Document: ALA4840316
Inhibition of 5-LO in A23187/AA-stimulated human intact neutrophils assessed as reduction in LTB4/5-HETE formation by measuring residual activity at 10 uM measured after 20 mins by RP-HPLC method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4840850
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 320.37 | 4.84 | 4.84 |
| 349.42 | 4.22 | 4.22 |
| 348.43 | 4.96 | 4.96 |
| 343.41 | 5.61 | 5.61 |
| 335.39 | 4.42 | 4.42 |
| 374.34 | 5.26 | 5.26 |
| 348.43 | 5.32 | 5.32 |
| 377.47 | 4.59 | 4.59 |
| 355.42 | 3.12 | 3.12 |
| 363.44 | 4.41 | 4.41 |
| 348.43 | 4.55 | 4.55 |