Inhibition of human recombinant DPP4 using Gly-Pro-AMC as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins b...

Basic Information

ID: ALA4841116

Type: Binding

Description: Inhibition of human recombinant DPP4 using Gly-Pro-AMC as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by fluorescence based microplate reader assay

Format: BAO_0000357

Organism: Homo sapiens

Target: Dipeptidyl peptidase IV(ALA284)

Document: ALA4840327

Inhibition of human recombinant DPP4 using Gly-Pro-AMC as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by fluorescence based microplate reader assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4841116

IC50

Total(36)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
303.41	1.17	1.17
339.40	0.39	0.39
352.44	1.01	1.01
444.92	1.45	1.45
428.46	0.93	0.93
396.45	0.71	0.71
489.37	1.56	1.56
489.37	1.56	1.56
415.50	1.91	1.91
459.51	1.60	1.60
489.37	1.56	1.56
475.34	1.47	1.47
473.53	1.69	1.69
459.51	1.60	1.60
414.44	0.85	0.85
481.55	0.30	0.30
467.53	0.21	0.21
493.56	0.70	0.70
459.51	1.60	1.60
475.34	1.47	1.47
410.47	0.80	0.80
414.44	0.85	0.85
489.37	1.56	1.56
473.53	1.69	1.69
430.89	1.36	1.36
507.59	0.79	0.79
507.59	0.79	0.79
453.50	-0.18	-0.18
473.53	1.69	1.69
428.46	0.93	0.93
493.56	0.70	0.70
475.34	1.47	1.47
467.53	-0.09	-0.09
475.34	1.47	1.47
428.46	0.93	0.93
414.44	0.85	0.85