Basic Information
ID: ALA4841596
Type: ADME
Description: Stability in mouse liver S9 fraction assessed as extraction ratio at 3 uM measured upto 45 mins in presence of NADPH and UDPGA by LC-MS/MS analysis
Format: BAO_0000220
Organism: Mus musculus
Tissue: Liver
Subcellular Fraction: S9 fraction
Target: ADMET(ALA612558)
Document: ALA4840350
Stability in mouse liver S9 fraction assessed as extraction ratio at 3 uM measured upto 45 mins in presence of NADPH and UDPGA by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4841596
ERH
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 403.44 | 4.14 | 4.14 |
| 363.39 | 4.55 | 4.55 |
| 387.34 | 5.43 | 5.43 |
| 375.45 | 5.67 | 5.67 |
| 365.38 | 5.31 | 5.31 |
| 351.36 | 4.68 | 4.68 |
| 385.35 | 4.84 | 4.84 |
| 379.39 | 4.25 | 4.25 |
| 317.37 | 4.84 | 4.84 |
| 379.39 | 4.25 | 4.25 |
| 320.33 | 3.64 | 3.64 |
| 345.40 | 4.41 | 4.41 |
| 334.35 | 3.94 | 3.94 |
| 367.81 | 5.20 | 5.20 |
| 335.34 | 3.33 | 3.33 |
| 381.43 | 3.94 | 3.94 |
| 347.39 | 4.85 | 4.85 |
| 357.39 | 4.42 | 4.42 |
| 370.33 | 4.53 | 4.53 |
| 334.35 | 3.94 | 3.94 |
| 347.39 | 4.93 | 4.93 |
| 335.34 | 3.33 | 3.33 |
| 365.38 | 5.25 | 5.25 |
| 345.38 | 4.47 | 4.47 |
| 413.40 | 5.62 | 5.62 |
| 445.44 | 6.80 | 6.80 |
| 388.43 | 4.06 | 4.06 |
| 389.76 | 5.48 | 5.48 |
| 376.37 | 4.87 | 4.87 |
| 370.33 | 4.53 | 4.53 |
| 367.36 | 4.70 | 4.70 |
| 363.39 | 4.55 | 4.55 |
| 333.37 | 4.54 | 4.54 |
| 349.37 | 4.24 | 4.24 |
| 404.43 | 4.19 | 4.19 |
| 365.38 | 5.31 | 5.31 |
| 419.35 | 6.02 | 6.02 |
| 281.33 | 3.96 | 3.96 |
| 385.80 | 5.65 | 5.65 |
| 413.40 | 5.62 | 5.62 |
| 417.47 | 4.20 | 4.20 |
| 361.40 | 4.11 | 4.11 |
| 387.34 | 5.28 | 5.28 |
| 415.37 | 5.00 | 5.00 |
| 355.32 | 4.83 | 4.83 |
| 383.37 | 5.44 | 5.44 |
| 423.32 | 5.85 | 5.85 |
| 439.50 | 3.55 | 3.55 |
| 340.38 | 2.27 | 2.27 |
| 421.33 | 5.59 | 5.59 |
| 347.35 | 4.26 | 4.26 |
| 331.38 | 4.10 | 4.10 |
| 370.33 | 4.53 | 4.53 |
| 369.35 | 5.14 | 5.14 |