Basic Information
ID: ALA4841646
Type: ADME
Description: Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate incubated for 10 mins in presence of NADPH by LC-MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 2D6(ALA289)
Document: ALA4840351
Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate incubated for 10 mins in presence of NADPH by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4841646
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 324.42 | 3.17 | 3.17 |
| 527.51 | 3.27 | 3.27 |