Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate incubated for 10 mins in presence of NADPH by LC-MS/MS analysis

Basic Information

ID: ALA4841647

Type: ADME

Description: Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate incubated for 10 mins in presence of NADPH by LC-MS/MS analysis

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Target: Cytochrome P450 2C19(ALA3622)

Document: ALA4840351

Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate incubated for 10 mins in presence of NADPH by LC-MS/MS analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4841647

IC50

Total(2)

Parent Molecular Weight	ALogP	Polar Surface Area
345.42	2.90	2.90
527.51	3.27	3.27

Parent Molecular Weight

ALogP

Polar Surface Area

345.42

2.90

527.51

3.27

Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate incubated for 10 mins in presence of NADPH by LC-MS/MS analysis

Basic Information

Activity Charts

Compound Summary