Inhibition of full-length N-terminal GST tagged BTK (2 to 659 residues) (unknown origin) expressed in Sf21 insect cells using NH2-ETVYSEVRK-biotin as ...

Basic Information

ID: ALA4841669

Type: Binding

Description: Inhibition of full-length N-terminal GST tagged BTK (2 to 659 residues) (unknown origin) expressed in Sf21 insect cells using NH2-ETVYSEVRK-biotin as substrate preincubated for 1 hr followed by ATP addition and measured after 2 hrs by ELISA

Format: BAO_0000219

Organism: Homo sapiens

Cell type: Sf21

Target: Tyrosine-protein kinase BTK(ALA5251)

Document: ALA4840351

Inhibition of full-length N-terminal GST tagged BTK (2 to 659 residues) (unknown origin) expressed in Sf21 insect cells using NH2-ETVYSEVRK-biotin as substrate preincubated for 1 hr followed by ATP addition and measured after 2 hrs by ELISA: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4841669

IC50

Total(55)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
440.51	4.22	4.22
465.52	3.31	3.31
471.56	4.22	4.22
459.51	2.25	2.25
473.54	2.56	2.56
501.59	3.20	3.20
539.52	3.11	3.11
529.52	3.49	3.49
582.06	4.41	4.41
547.62	3.75	3.75
473.54	2.56	2.56
505.97	2.74	2.74
560.62	3.79	3.79
473.54	2.42	2.42
484.52	2.12	2.12
550.42	2.85	2.85
465.54	2.31	2.31
473.54	1.98	1.98
597.42	2.69	2.69
501.55	2.10	2.10
487.56	2.81	2.81
445.48	1.86	1.86
515.62	3.59	3.59
493.96	2.90	2.90
572.63	3.63	3.63
515.62	3.59	3.59
460.50	1.64	1.64
535.61	3.92	3.92
553.60	4.06	4.06
527.51	3.27	3.27
565.61	3.89	3.89
487.56	2.46	2.46
499.58	2.46	2.46
493.96	2.90	2.90
485.55	2.40	2.40
499.58	2.65	2.65
496.53	1.96	1.96
459.51	2.25	2.25
491.53	2.70	2.70
471.52	2.09	2.09
585.41	2.85	2.85
485.55	2.40	2.40
489.54	2.26	2.26
472.51	1.48	1.48
556.55	4.35	4.35
458.52	2.85	2.85
485.55	2.26	2.26
501.59	3.20	3.20
501.59	3.20	3.20
554.66	3.73	3.73
552.64	3.49	3.49
503.54	2.53	2.53
538.41	3.01	3.01
501.59	3.37	3.37
570.05	4.57	4.57