Basic Information
ID: ALA4841671
Type: Binding
Description: Inhibition of full-length N-terminal GST-tagged ITK (2 to 620 residues) (unknown origin) expressed in Sf21 insect cells using NH2-ETVYSEVRK-biotin as substrate preincubated for 1 hr followed by ATP addition and measured after 2 hrs by ELISA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf21
Target: Tyrosine-protein kinase ITK/TSK(ALA2959)
Document: ALA4840351
Inhibition of full-length N-terminal GST-tagged ITK (2 to 620 residues) (unknown origin) expressed in Sf21 insect cells using NH2-ETVYSEVRK-biotin as substrate preincubated for 1 hr followed by ATP addition and measured after 2 hrs by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4841671
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 440.51 | 4.22 | 4.22 |
| 465.52 | 3.31 | 3.31 |
| 471.56 | 4.22 | 4.22 |
| 539.52 | 3.11 | 3.11 |
| 547.62 | 3.75 | 3.75 |
| 505.97 | 2.74 | 2.74 |
| 493.96 | 2.90 | 2.90 |
| 535.61 | 3.92 | 3.92 |
| 553.60 | 4.06 | 4.06 |
| 527.51 | 3.27 | 3.27 |
| 489.54 | 2.26 | 2.26 |
| 538.41 | 3.01 | 3.01 |
| 570.05 | 4.57 | 4.57 |