Basic Information
ID: ALA4842477
Type: Binding
Description: Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AMC as a substrate measured over 30 mins by fluorometric assay
Organism: Plasmodium falciparum
Activity Charts
Bioactivity
Activity Types for Assay ALA4842477
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 284.35 | 2.19 | 2.19 |
| 896.03 | 8.16 | 8.16 |
| 896.03 | 8.16 | 8.16 |
| 869.99 | 7.67 | 7.67 |
| 545.63 | 4.16 | 4.16 |
| 904.01 | 7.87 | 7.87 |
| 869.99 | 7.67 | 7.67 |
| 896.03 | 8.16 | 8.16 |
| 519.59 | 3.68 | 3.68 |
| 692.81 | 4.89 | 4.89 |
| 269.28 | 3.47 | 3.47 |
| 666.77 | 4.41 | 4.41 |
| 930.05 | 8.36 | 8.36 |
| 632.75 | 4.21 | 4.21 |
| 782.87 | 7.63 | 7.63 |
| 904.01 | 7.87 | 7.87 |
| 869.99 | 7.67 | 7.67 |
| 658.79 | 4.69 | 4.69 |
| 756.83 | 7.14 | 7.14 |
| 904.01 | 7.87 | 7.87 |