ID: ALA4842478
Type: Binding
Description: Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AMC as a substrate measured over 30 mins by Cheng-prusoff equation analysis
Organism: Plasmodium falciparum
Bioactivity
Activity Types for Assay ALA4842478
Ki
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
284.35 | 2.19 | 2.19 |
896.03 | 8.16 | 8.16 |
896.03 | 8.16 | 8.16 |
869.99 | 7.67 | 7.67 |
545.63 | 4.16 | 4.16 |
904.01 | 7.87 | 7.87 |
869.99 | 7.67 | 7.67 |
896.03 | 8.16 | 8.16 |
519.59 | 3.68 | 3.68 |
692.81 | 4.89 | 4.89 |
269.28 | 3.47 | 3.47 |
666.77 | 4.41 | 4.41 |
930.05 | 8.36 | 8.36 |
632.75 | 4.21 | 4.21 |
782.87 | 7.63 | 7.63 |
904.01 | 7.87 | 7.87 |
869.99 | 7.67 | 7.67 |
658.79 | 4.69 | 4.69 |
756.83 | 7.14 | 7.14 |
904.01 | 7.87 | 7.87 |