Assay Report Card

Basic Information

ID: ALA4842478

Type: Binding

Description: Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AMC as a substrate measured over 30 mins by Cheng-prusoff equation analysis

Organism: Plasmodium falciparum

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
284.352.192.19
896.038.168.16
896.038.168.16
869.997.677.67
545.634.164.16
904.017.877.87
869.997.677.67
896.038.168.16
519.593.683.68
692.814.894.89
269.283.473.47
666.774.414.41
930.058.368.36
632.754.214.21
782.877.637.63
904.017.877.87
869.997.677.67
658.794.694.69
756.837.147.14
904.017.877.87