Basic Information
ID: ALA4843236
Type: Binding
Description: Inhibition of recombinant human His-tagged IDO1 (Ala2 to Gly403 residues) expressed in Escherichia coli using tryptophan as substrate preincubated for 10 mins followed by substrate addition and measured after 1 hr by RFMS assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Indoleamine 2,3-dioxygenase(ALA4685)
Document: ALA4842341
Inhibition of recombinant human His-tagged IDO1 (Ala2 to Gly403 residues) expressed in Escherichia coli using tryptophan as substrate preincubated for 10 mins followed by substrate addition and measured after 1 hr by RFMS assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4843236
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.24 | 0.42 | 0.42 |
| 316.38 | 2.89 | 2.89 |
| 232.21 | 1.44 | 1.44 |
| 420.94 | 5.50 | 5.50 |
| 381.36 | 2.17 | 2.17 |
| 393.92 | 5.76 | 5.76 |
| 394.90 | 5.85 | 5.85 |
| 406.91 | 5.85 | 5.85 |
| 381.36 | 2.17 | 2.17 |
| 327.86 | 5.64 | 5.64 |
| 420.94 | 5.50 | 5.50 |
| 395.89 | 4.23 | 4.23 |