Basic Information
ID: ALA4843239
Type: ADME
Description: Intrinsic clearance in human liver microsomes at 1 uM measured up to 45 mins in presence of NADPH by LC-MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: ADMET(ALA612558)
Document: ALA4842341
Intrinsic clearance in human liver microsomes at 1 uM measured up to 45 mins in presence of NADPH by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4843239
CL
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.24 | 0.42 | 0.42 |
| 316.38 | 2.89 | 2.89 |
| 232.21 | 1.44 | 1.44 |
| 438.93 | 5.64 | 5.64 |
| 384.91 | 4.21 | 4.21 |
| 439.92 | 4.59 | 4.59 |
| 419.93 | 6.84 | 6.84 |
| 420.94 | 5.50 | 5.50 |
| 429.90 | 5.37 | 5.37 |
| 410.88 | 4.86 | 4.86 |
| 416.46 | 3.86 | 3.86 |
| 381.36 | 2.17 | 2.17 |
| 419.92 | 4.36 | 4.36 |
| 415.90 | 3.84 | 3.84 |
| 410.92 | 6.58 | 6.58 |
| 429.90 | 5.37 | 5.37 |
| 393.92 | 5.76 | 5.76 |
| 408.90 | 5.59 | 5.59 |
| 394.91 | 4.49 | 4.49 |
| 429.90 | 5.37 | 5.37 |
| 415.87 | 4.98 | 4.98 |
| 412.90 | 4.63 | 4.63 |
| 462.81 | 6.40 | 6.40 |
| 401.84 | 4.60 | 4.60 |
| 384.91 | 4.21 | 4.21 |
| 394.91 | 4.49 | 4.49 |
| 411.91 | 5.23 | 5.23 |
| 411.91 | 5.23 | 5.23 |
| 411.91 | 5.23 | 5.23 |
| 438.93 | 5.64 | 5.64 |
| 394.90 | 5.85 | 5.85 |
| 406.91 | 5.85 | 5.85 |
| 381.36 | 2.17 | 2.17 |
| 418.93 | 4.97 | 4.97 |
| 421.93 | 4.90 | 4.90 |
| 429.90 | 5.37 | 5.37 |
| 327.86 | 5.64 | 5.64 |
| 420.94 | 5.50 | 5.50 |
| 410.88 | 4.86 | 4.86 |
| 455.86 | 6.06 | 6.06 |
| 411.91 | 5.23 | 5.23 |
| 421.93 | 4.90 | 4.90 |
| 410.88 | 4.86 | 4.86 |
| 438.93 | 5.64 | 5.64 |
| 394.91 | 4.49 | 4.49 |
| 395.89 | 4.23 | 4.23 |
| 393.92 | 5.10 | 5.10 |
| 419.92 | 4.36 | 4.36 |