Basic Information
ID: ALA4843280
Type: ADME
Description: Inhibition of CYP2C9 in human liver microsomes using sulfaphenazole as substrate incubated for 10 mins in presence of NADPH by LCMS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4843280
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.24 | 0.42 | 0.42 |
| 419.93 | 6.84 | 6.84 |
| 429.90 | 5.37 | 5.37 |
| 381.36 | 2.17 | 2.17 |
| 419.92 | 4.36 | 4.36 |
| 410.92 | 6.58 | 6.58 |
| 429.90 | 5.37 | 5.37 |
| 408.90 | 5.59 | 5.59 |
| 394.91 | 4.49 | 4.49 |
| 429.90 | 5.37 | 5.37 |
| 415.87 | 4.98 | 4.98 |
| 429.90 | 5.37 | 5.37 |
| 412.90 | 4.63 | 4.63 |
| 462.81 | 6.40 | 6.40 |
| 401.84 | 4.60 | 4.60 |
| 394.91 | 4.49 | 4.49 |
| 411.91 | 5.23 | 5.23 |
| 411.91 | 5.23 | 5.23 |
| 381.36 | 2.17 | 2.17 |
| 418.93 | 4.97 | 4.97 |
| 429.90 | 5.37 | 5.37 |
| 455.86 | 6.06 | 6.06 |
| 411.91 | 5.23 | 5.23 |
| 394.91 | 4.49 | 4.49 |
| 393.92 | 5.10 | 5.10 |
| 394.91 | 4.49 | 4.49 |
| 419.92 | 4.36 | 4.36 |