Basic Information
ID: ALA4843302
Type: Functional
Description: In vivo inhibition of IDO1 in tumor of NSG mouse xenografted with human SKOV3 cells assessed as KYN level at 125 mg/kg, po BID administered for 5 days and measured 24 hrs post dose
Format: BAO_0000218
Organism: Mus musculus
Strain: NSG
Cell type: SK-OV-3
Target: Indoleamine 2,3-dioxygenase 1(ALA1075294)
Document: ALA4842341
In vivo inhibition of IDO1 in tumor of NSG mouse xenografted with human SKOV3 cells assessed as KYN level at 125 mg/kg, po BID administered for 5 days and measured 24 hrs post dose: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4843302
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.24 | 0.42 | 0.42 |
| 381.36 | 2.17 | 2.17 |
| 381.36 | 2.17 | 2.17 |