Basic Information
ID: ALA4843303
Type: Functional
Description: In vivo inhibition of IDO1 in tumor of NSG mouse xenografted with human SKOV3 cells assessed as KYN level at 125 mg/kg, po QD administered for 5 days and measured 24 hrs post dose
Format: BAO_0000218
Organism: Mus musculus
Strain: NSG
Cell type: SK-OV-3
Target: Indoleamine 2,3-dioxygenase 1(ALA1075294)
Document: ALA4842341
In vivo inhibition of IDO1 in tumor of NSG mouse xenografted with human SKOV3 cells assessed as KYN level at 125 mg/kg, po QD administered for 5 days and measured 24 hrs post dose: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4843303
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 418.93 | 4.97 | 4.97 |
| 415.87 | 4.98 | 4.98 |
| 410.92 | 6.58 | 6.58 |
| 415.87 | 4.98 | 4.98 |
| 429.90 | 5.37 | 5.37 |
| 428.36 | 5.75 | 5.75 |
| 425.94 | 5.54 | 5.54 |
| 447.89 | 5.51 | 5.51 |