Basic Information
ID: ALA4843308
Type: Functional
Description: In vivo inhibition of IDO1 in tumor of po dosed NSG mouse xenografted with human SKOV3 cells assessed as reduction in KYN level administered twice daily for 5 days measured at 12 hrs post dose
Format: BAO_0000218
Organism: Mus musculus
Strain: NSG
Tissue: Neoplasm
Cell type: SK-OV-3
Target: Indoleamine 2,3-dioxygenase 1(ALA1075294)
Document: ALA4842341
In vivo inhibition of IDO1 in tumor of po dosed NSG mouse xenografted with human SKOV3 cells assessed as reduction in KYN level administered twice daily for 5 days measured at 12 hrs post dose: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4843308
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 410.92 | 6.58 | 6.58 |