Metabolic stability in human liver microsomes assessed as half life at 100 uM in the presence of NADPH measured upto 60 mins by LC-MS/MS analysis

Basic Information

ID: ALA4843548

Type: ADME

Description: Metabolic stability in human liver microsomes assessed as half life at 100 uM in the presence of NADPH measured upto 60 mins by LC-MS/MS analysis

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Target:  ADMET(ALA612558)

Document:  ALA4842346

Metabolic stability in human liver microsomes assessed as half life at 100 uM in the presence of NADPH measured upto 60 mins by LC-MS/MS analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
365.454.534.53
416.434.604.60
379.464.924.92
303.363.403.40
416.434.604.60