Basic Information
ID: ALA4843592
Type: Binding
Description: Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein between exogenous [3H]LDL in 95% human serum by liquid scintillation analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: Cholesteryl ester transfer protein(ALA3572)
Document: ALA4842348
Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein between exogenous [3H]LDL in 95% human serum by liquid scintillation analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4843592
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 619.52 | 9.62 | 9.62 |
| 637.51 | 9.76 | 9.76 |
| 649.53 | 10.08 | 10.08 |
| 595.56 | 9.37 | 9.37 |
| 599.52 | 9.20 | 9.20 |
| 581.53 | 9.06 | 9.06 |
| 582.42 | 9.35 | 9.35 |
| 615.97 | 9.71 | 9.71 |
| 625.59 | 8.52 | 8.52 |
| 599.52 | 9.20 | 9.20 |
| 625.59 | 8.52 | 8.52 |
| 626.57 | 7.92 | 7.92 |
| 648.54 | 9.65 | 9.65 |
| 684.60 | 8.78 | 8.78 |
| 700.64 | 8.16 | 8.16 |
| 621.62 | 6.39 | 6.39 |
| 673.61 | 8.51 | 8.51 |
| 633.53 | 10.30 | 10.30 |
| 588.61 | 6.25 | 6.25 |
| 714.66 | 8.55 | 8.55 |
| 709.59 | 9.06 | 9.06 |
| 636.63 | 6.87 | 6.87 |
| 713.55 | 8.96 | 8.96 |
| 712.57 | 9.57 | 9.57 |
| 649.53 | 9.91 | 9.91 |
| 712.57 | 9.57 | 9.57 |
| 688.63 | 8.01 | 8.01 |
| 638.62 | 7.13 | 7.13 |
| 714.54 | 8.36 | 8.36 |
| 655.07 | 7.65 | 7.65 |
| 621.62 | 6.39 | 6.39 |
| 587.08 | 6.63 | 6.63 |
| 662.57 | 9.99 | 9.99 |
| 730.66 | 7.78 | 7.78 |
| 665.59 | 10.79 | 10.79 |
| 648.54 | 10.09 | 10.09 |
| 647.55 | 9.90 | 9.90 |
| 713.55 | 8.96 | 8.96 |
| 636.63 | 6.87 | 6.87 |
| 743.58 | 8.97 | 8.97 |
| 621.62 | 6.39 | 6.39 |
| 712.57 | 9.57 | 9.57 |
| 620.63 | 6.99 | 6.99 |
| 616.96 | 9.11 | 9.11 |
| 718.63 | 8.10 | 8.10 |
| 713.55 | 8.96 | 8.96 |
| 716.00 | 10.82 | 10.82 |
| 621.52 | 7.28 | 7.28 |
| 675.58 | 7.95 | 7.95 |