Basic Information
ID: ALA4843797
Type: ADME
Description: Time dependent inhibition of recombinant human CYP3A4 expressed in Escherichia coli using DEF as probe substrate preincubated for 10 mins followed by NADPH-regenerating system addition and measured at 1 min interval for 30 mins by fluorescence plate reader analysis
Format: BAO_0000019
Organism: Homo sapiens
Target: Cytochrome P450 3A4(ALA340)
Document: ALA4842350
Time dependent inhibition of recombinant human CYP3A4 expressed in Escherichia coli using DEF as probe substrate preincubated for 10 mins followed by NADPH-regenerating system addition and measured at 1 min interval for 30 mins by fluorescence plate reader analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4843797
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 450.54 | 4.97 | 4.97 |